I am a theoretician with a broad range of interests across ecology and evolution. In particular, I am interested in the role that defensive symbiosis can play on the evolution of pathogen virulence, and the effects that this has on the host population. I have also conducted modelling for various aspects of the COVID-19 pandemic, and am interested in general method formulation.
Publications
C.A. Smith,B Ashby. 2023. Tolerance conferring defensive symbionts and the evolution of parasite virulence. Evolution Letters 7, 262-272.
B. Ashby, C.A. Smith, R.N. Thompson. 2023. Non-pharmaceutical interventions and the emergence of pathogen variants. Evolution, Medicine and Public Health 11, 80-89.
C.A. Smith, B. Ashby. 2023. Antigenic evolution of SARS-CoV-2 in immunocompromised hosts. Evolution, Medicine and Public Health 11, 90-100.
C.A. Smith, C.A. Yates, B. Ashby. 2022. Critical weaknesses in shielding strategies for COVID-19. PLOS Global Public Health2, e0000298.
C.A Smith, C.A. Yates. 2021. Incorporating domain growth into hybrid methods for reaction-diffusion systems. Journal of the Royal Society: Interface 18, 20201047.
C.A. Yates, A. George, A. Jordana, C.A. Smith, A.B. Duncan and K.C. Zygalakis. 2020. The blending region hybrid framework for the simulation of stochastic reaction–diffusion processes. Journal of the Royal Society: Interface 17, 20200563.
C.A. Smith, C. Mailler, C.A. Yates. 2019. Unbiased on-lattice domain growth. Physical Review E 100:063307.
C.A.Smith, C.A. Yates. 2018. The auxiliary region method: a hybrid method for coupling PDE- and Brownian-based dynamics for reaction–diffusion systems. Royal Society Open Science 5:180920.
C.A.Smith, C.A. Yates. 2018. Spatially extended hybrid methods: a review. Journal of the Royal Society: Interface 15:20170931.